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18 GaoF.ChenJ.MaT

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14.4% in the per-protocol analysis (RR = 0.51

This method entails the co-encapsulation of LTX-315, a pioneering oncolytic cationic peptide, and TGF-1-targeting siRNA within a polymer-lipid hybrid nanoparticle formed from PLGA, DSPE-mPEG, and DSPE-PEG coupled with a cRGD peptide (designated as LTX/siR-NPs)

Iodoacetamide was added to 10 mM and incubated in the dark at room temperature for 30 min to alkylate the proteins

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