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The development of GLP-1 medicines has transformed the therapeutic options for patients with type 2 diabetes (T2D) who are unable to achieve sufficient glucose control with existing treatments

Use consistent tools such as bioelectrical impedance, skinfold calipers, or DXA when available

coli and diarrhea caused by GLP-1RA use is an issue for future study

Regulation of glucose homeostasis by GLP-1

Retatrutide is being studied because researchers are evaluating whether adding glucagon receptor activity may further influence energy expenditure and weight reduction

Glucagon increases energy expenditure by promoting thermogenesis in brown fat tissue