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Request a medical necessity letter if your plan does not list Ozempic, with lab results and prior therapy documentation

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13 While native GLP-1 has been targeted as a therapeutic agent due to its favorable effects on glycemia, its clinical utility is limited due to its extremely short half-life

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Its stability-enhancing N-terminal modification allows for effective subcutaneous administration, and it is FDA-approved for HIV-related lipodystrophy.