TRIUMPH-2: obesity with type 2 diabetes
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Because of this, retatrutide is often discussed as a next-generation option rather than a currently accessible treatment
Tirzepatide was associated with numerically greater weight loss across available studies, though high heterogeneity and observational data limit causal inference
I might suggest this approach to a patient who is having difficulty with side effects, or someone who is having brisk weight loss on low doses
Most of it is water and reduced food volume, not fat