In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]
Patients survived for an average of 6.9 months without disease progression, and 13.4 months overall
If digestion slows too much, gastroparesis (also known as delayed gastric emptying) and gastroenteritis (among other side effects, some life-threatening like ileus which is similar to gastroparesis but happens in the intestines,) can occur
Rikkunshito improves the symptoms in patients with functional dyspepsia, accompanied by an increase in the level of plasma ghrelin
Synergy: The GIP component seems to mitigate some of the nausea associated with high-dose GLP-1, allowing patients to tolerate higher effective doses for greater weight loss
Start meals with protein Begin each meal with your protein source to maximize intake despite reduced appetite on GLP-1 medications
