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There are several Phase 3 trials evaluating GLP-1s for conditions, such as metabolic dysfunction-associated steatohepatitis (MASH), prediabetes, Alzheimer's disease, diabetic retinopathy and osteoarthritis of the knee (in patients with obesity)
10.1016/j.neuron.2013.03.021 133 XuX.HuangE.LuoB.CaiD.ZhaoX.LuoQ.et al (2018)
Selenium in colorectal and differentiated thyroid cancer
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The publication of high-quality mechanistic studies, coupled with small human trials showing functional endocrine and immune effects , has elevated the peptide from fringe curiosity to a serious candidate in the longevity toolkit
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