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Immunomodulators: For severe or resistant rashes, topical immunomodulators like tacrolimus or pimecrolimus may be prescribed

These molecules interact with cytokines critical to the development and persistence of skin disease, such as TNF-, IL-23, IL-17 and IL-22

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Glucagon-like Peptide-1 Receptor Agonists Suppress Water Intake Independent of Effects on Food Intake. American Journal of Physiology

Furthermore, in appendiceal ligation and puncture-mediated sepsis, investigators found a decrease in GSH content and GPX4 expression and an accumulation of cardiac iron content and lipid peroxidation levels [94]