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[4] Patients should never adjust dosing of either medication without medical supervision and should report any concerning symptoms to their healthcare provider promptly

In a retrospective study wherein BMI was used as a proxy for adiposity (median age 40 yr, range 2077 yr, median BMI 26 kg/m2, range 18.349.8 kg/m2), total and pulsatile 24 hour GH secretion were both negatively associated with BMI, and GH secretion was higher in women than men below 50 years of age, likely due to the influence of estradiol levels on IGF-1 levels (22) (Figures 3,4)

Always coordinate with your prescriber

Even when you understand the science and know it is temporary, watching your hair thin is distressing

Sterile water reconstitutions should be used within 24 hours

Sema was given twice per week for 20 weeks, starting on Day 0 of the study at 10 g/kg, and no titration of Sema was given due to the low dose regimen