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CCDS3, caused by genetic variants in the AGAT gene, is an autosomal recessive inherited metabolic disorder

Never stop alprazolam abruptly without medical supervision, as benzodiazepine withdrawal can be dangerous

The exact pathophysiology involves increased intraluminal pressure, weakening of the colonic wall, and alterations in gut microbiota, though the precise mechanisms remain under investigation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Artigas CF, Stokes V, Tan GD, Theodorakis MJ

It works by mimicking two natural hormones in the body: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)