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In addition, probiotics can stimulate the hosts antioxidant defence systems and increase the activity of antioxidant enzymes (224)

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These facts, together with increasing comorbidities in patients with IBD, imply that urgent, more complex, novel therapeutic strategies in the treatment are needed

When it occurs, it is typically temporary and linked to digestion or hydration changes early in treatment

Ketamine is endowed with a peculiar profile with multiple pharmacological activities that may result from different underlying mechanisms