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A total of 40 mice were utilized, with 20 mice induced with EAE receiving 25 nmol/kg/day i.p

10.1016/j.stem.2016.04.015 50 KhachoM.HarrisR.SlackR

While not a direct side effect, some patients may experience musculoskeletal pain, which can include back pain, possibly due to weight loss or changes in body composition

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StatPearls: Elimination Half-Life of Drugs (NCBI Bookshelf)Supports: A medication is commonly considered essentially eliminated after four to five half-lives, when about 94 to 97% has left the system.