Sharma P, PhD, Piya S, PhD, Ma H, MS, Baran N, PhD, MD, Zal MA, MSc, Hindley CJ, PhD, Dao K, DO, Sims M, PhD, Zal T, PhD, MSc, Ruvolo V, MS, Andreeff M , MD, PhD, Borthakur G, MD
In ALCAR-treated xenografts, we observed a trend toward a reduced microvascular density, as revealed by histology (Additional file 1: Figure S4)
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Journal of Trace Elements in Medicine and Biology, 28, 266-270
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Synergistic interactions of N-3 PUFAs with multiple nuclear receptors, in particular PPAR- and RXR, might amplify VDR signaling further, as N-3 PUFAs promote PPAR-/PGC-1 pathways 115,116 and stabilize VDR-RXR heterodimers, which are critical for the VDR transcriptional activity 117,118
