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All clinical trial protocols used once-weekly subcutaneous injection

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Mol Metab 30:72130 Foer D, Beeler PE, Cui J, Karlson EW, Bates DW, Cahill KN (2021) Asthma exacerbations in patients with type 2 diabetes and asthma on Glucagon-like Peptide-1 receptor agonists

Its mechanism involves modulation of the hypothalamic-pituitary-adrenal (HPA) axis, regulation of cortisol and growth hormone-releasing hormone (GHRH) secretion, and interaction with the GABAergic and glutamatergic systems

Monotherapy profile Cagrilintide as a standalone compound shows a remarkably favorable tolerability profile