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Follistatin is more immediately useful as a research target and a potential biomarker of PCOS severity than as a near-term treatment option
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Fujimura, Y
This comprehensive mechanism addresses appetite, energy expenditure, gastric function, and glucose homeostasis through distinct but complementary receptor systems, potentially explaining enhanced efficacy observed in combination approaches compared to monotherapies
Subsequently, the blots proceeded through a second round of immunodetection by agitating for 45 min at 50C in stripping buffer (2% SDS, 0.8% -mercaptoethanol (ME), and 62.5 mM Tris-HCl, pH 6.8) 32,56,62 followed by re-probing with HRP-labeled anti-HGF N -terminal domain mAb (1:2500 dilution in CanGetSignal solution 1) to monitor HGF -chain amount on the blots as loading controls