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10.3390/ijms20020263 183 YeJ.QiL.ChenK.LiR.SongS.ZhouC.et al (2019)

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Metabolite sensing mechanisms and switches (such as O-GlcNAcylation, N-acylation, lactylation and methylation) have been discovered to dynamically regulate the epigenetic programming of particular lineages cell fates during fetoplacental development

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(8) Notably, when both agents were combined in laboratory settings, the outcome was apparently a 54-fold upregulation in pulsatile growth hormone output