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trial, subjects receiving weekly doses of 30 to 60 mcg/kg (roughly 2,000 to 4,000 mcg for an 80 kg adult) showed sustained IGF-1 elevation with no serious adverse events over the study period (Teichman et al., J Clin Endocrinol Metab 2006)

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Korphaisarn K, Lam M, Loree JM, Ruiz E, Aguiar S, Kopetz S

conducted a 2-year follow-up survey of 490 subjects over 60 years of age with cognitive performance and blood tests