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Furthermore, the Keap1/NRF2/ARE signaling pathway plays a critical role in tumor cell drug resistance, and PVT1 may further promote the development of resistance by regulating this pathway [169]

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Patients with obesity and metabolic syndrome : Weight reduction achieved through GLP-1 therapy often correlates with improvements in the characteristic dyslipidaemia of metabolic syndrome (elevated triglycerides, low HDL cholesterol, and small dense LDL particles)

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& Revial, M.-F