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Phase 2 Trial Data, What Researchers Are Working From The pivotal Phase 2 trial (Jastreboff et al., NEJM 2023, NCT04881760) enrolled 338 adults across six cohorts over 48 weeks

A review of the effects of glucagon-like Peptide-1 receptor agonists and sodium-glucose cotransporter 2 inhibitors on lean body mass in humans

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The compound is administered as a subcutaneous injection once weekly, similar to Semaglutide and Tirzepatide

It is possible that subpopulations of these cells exist, each with distinct roles in energy homeostasis