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HEK-293 cells (ATCC, #CRL-1573) were cultured in DMEM medium (Gibco) supplemented with 10% FBS and 100 U/mL penicillin/streptomycin

Other health risks include pancreatitis, thyroid cancer, kidney failure, gallbladder disease, changes in vision, hypoglycemia (low blood sugar), and allergic reactions

Common side effectsnausea, constipation, and decreased appetiteare not related to kidney problems

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An arterial blood gas revealed a pH of 7.40, PaCO2 25mmHg, Bicarbonate 13mmol/L and PaO2 100mmHg

However, a study published in Diabetes, Obesity and Metabolism found that many patients who discontinue these medications either restart treatment or switch to other options within a year