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Although autonomic and peripheral GLP-1R+ neurons, including those within the nodose ganglion, may partially contribute to the weight loss actions of peripherally administered GLP-1RA [74, 82], ablation of CNS neurons targeted by nestin - Cre or Wnt1 - Cre abolishes the anorectic actions of peripherally administered GLP-1RA in mice [74, 83]

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