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doi: 10.1002/cam4.2108 175 HanSLinFQiYLiuCZhouLXiaYet al

Stage IV: Immunotherapy: Checkpoint inhibitors (e.g., pembrolizumab, nivolumab, or nivolumab plus ipilimumab) to enhance immune response against cancer cells

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You can't just have a bunch of cells with a bunch of empty space around them where they can move about

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