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Mitochondria as signaling organelles control mammalian stem cell fate

Whether this translates into the direct-comparison advantage implied by network meta-analyses will remain open until a head-to-head RCT reads out which, as of April 2026, none has been announced

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The proposed mechanism involves MMP-1, a specific matrix metalloproteinase

The effect of EDTA-based chelation on patients with diabetes and peripheral artery disease in the Trial to Assess Chelation Therapy (TACT) J Diabetes Complications

That is a goal worthy of the integrated approach the evidence is beginning to support