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This is accompanied by loss of the glycocalyx and a 60% increase in permeability of the vascular endothelium, a change that is even more pronounced in patients who die as a result of sepsis, indirectly demonstrating that sepsis leads to the degradation of the glycocalyx and a compensatory increase in glycocalyx synthesis by endothelial cells (60)
10.1016/j.sajb.2007.03.006 116 NiehlA.LacommeC.ErbanA.KopkaJ.KrmerU.FisahnJ
Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration
Antioxidants 11 , 812834 (2022)
15,34,62 Protect against further nerve damage - by reducing oxidative stress & pro-inflammatory markers
GHK (glycyl-L-histidyl-L-lysine) peptide has been shown to positively influence gene expression by regulating various cellular pathways associated with tissue repair, wound healing, and anti-aging mechanisms [7], and thus has potential as an anti-fibrotic agent
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