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344,345,346 Although some studies indicate that breast cancer patients with ER expression between 1% and 10% may exhibit reduced sensitivity to endocrine therapy, the threshold of 1% ER expression is still used in most current clinical practices to determine the need for endocrine therapy

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Pei L, Tontonoz P

Adv Drug Deliv Rev 97:4155

By serving as a direct precursor to glutathione, the body's master antioxidant, NAC offers a targeted approach to supporting liver detoxification, neutralizing neuroinflammation, and rescuing exhausted cellular energy pathways