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Genetic mutations in PINK1 and PARKIN, which regulate mitophagy, impair the clearance of damaged mitochondria, exacerbating oxidative stress (Franco et al., 2021

Nature 447 , 864868 (2007)

In theory, more carnitine means better fat oxidation, better endurance, and maybe even less lactate buildup during high-intensity work, she explains

Unlike other GH secretagogues, it is noted for its selectivity, meaning it primarily stimulates the release of growth hormone without significantly affecting other hormones like cortisol or prolactin, thereby reducing the likelihood of unwanted side effects

Most of what we know comes from preclinical and experimental research, rather than human trials

Systematic review A total of 21 CEAs (including the present study) were identified in the systematic review (Additional file 1: Fig