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Since vinculin plays a key role in regulating gut motility, damage to it can cause a permanently weakened MMC, reducing the guts ability to clear bacteria and archaea and setting the stage for chronic, relapsing SIBO
The medication may cause persistent nausea, vomiting, abdominal pain, or fatigue that interferes with daily life
These findings were in line with the histopathological findings, which revealed perivascular and interstitial mixed inflammatory cell infiltration along with vasodilation
Before GLP-1s, medicines that targeted inflammation like steroids worked by shutting it down, suppressing the immune system and making patients more vulnerable to infections and cancer
Gusterson et al
Its also possible that GLP-1s can lessen PCOS symptoms in ways that arent directly tied to weight
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