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Ozempic and similar drugs are prescription GLP-1 receptor agonists that directly activate GLP-1 receptors

These cases are incredibly complex

In a 2024 literature review published in the Journal of the American Pharmacists Association that assessed six clinical trials , researchers found that tirzepatide had a greater impact on absorption of oral hormonal contraceptives compared with other GLP-1s

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Some people report feeling persistently cold whilst taking these medications, although this is not listed as an official adverse effect in the Summary of Product Characteristics (SmPC) for these products