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In one clinical trial, EGCG is able to decrease albuminuria and ameliorate DKD ( via inhibiting Keap1 and upregulating Nrf2-ARE signaling pathway (Wang et al., 2015c

doi: 10.1007/s00394-020-02199-z 26

Clinical evidence demonstrates that oral doses of 13 grams per day, administered for 612 months, can reduce neuropathic pain scores, with enhancements in nerve fiber regeneration and sensory function, particularly when combined with standard therapies [5]

Ideal candidates often include people who have already tried conservative treatments such as physical therapy, stretching routines, or over-the-counter anti-inflammatories (like NSAIDs) without lasting relief

Freezing and Thawing Freezing : Freeze the aliquots quickly by placing them in an ethanol/dry ice bath or a specialized freezer rack to avoid degradation