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A central, unresolved question remains how to precisely balance the modulation of autophagy and ferroptosis to maximize therapeutic efficacy while minimizing the risks of tumor promotion or off-target tissue damage

Nootropics are products, including natural and manmade dietary supplements, that are used to boost cognitive performance

in vitro experiments demonstrated that SGK1 knockdown attenuated erastin-induced downregulation of Slc7a11, GPX4, GSH, and oxidized glutathione (GSSG), while reducing lipid peroxidation, iron accumulation, and mitochondrial damage upregulation, suggesting SGK1's critical role in CHD-associated ferroptosis (44)

(6) Such findings might reflect an increase in somatotroph cell populationsthe specialized pituitary cells primarily associated with synthesizing and releasing growth hormone

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We, therefore, aimed to systematically review the molecular and pathophysiological mechanisms of hyperprolactinemia and obesity, focusing on key central and peripheral pathways, supported by current experimental and clinical evidence ( Figure 1 )