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Many people maintain adequate B12 levels throughout their semaglutide treatment, especially those who start with robust B12 stores, eat a varied diet including animal products, and are not taking other B12-depleting medications

All described studies evaluating small intestinal permeability used a 5 or 6 h urinary collection to assess small intestinal permeability, which may have confounded the results since a large amount of the sugars were probably already localized in the colon by the end of the urine collection (33)

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