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Obes Surg 34(7):23692374

The LEAN-PREP study (NCT enrolling 2025) is the first, with results expected 2026-2027

The Bottom Line GLP-1s offer meaningful protection against serious cardiovascular events like heart attacks and strokes

As your health improves and your body responds to treatment, your plan is continuously refined to keep your progress consistent and your results sustainable

Behavior Change Group Better Maintains Weight Loss 11 11 6 out of 7 people stop taking GLP-1s 12

This revealed an interaction between the metabolite and mitochondrial trifunctional protein- (MTP), which is known to regulate fatty acid oxidation (FAO) (23)