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They have alterations in their gut microbiome and metabolic hormones

Previous studies have proposed a correlation between increased incidence of IBD and PUFA (such as Aa) intake in the diet [293]

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Early detection and a treatment may improve the quality of life and prolong the survival of patients

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DHAR and GR activities convert the DHA translocated from the lumen and the DHA generated in the stroma to AsA (Asada, AsA-GSH pathway in mitochondria The presence and activity of AsA-GSH cycle enzymes in mitochondria of plant cells have been established, and this cycle plays an important role in protecting mitochondrion against the toxic ROS regularly produced in respiratory chain reactions (Leonardis et al., 2000