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Rare but serious reactions can include trouble breathing, wheezing, chest tightness, severe dizziness, fainting, or severe allergic reaction with swelling of the face, lips, tongue, or throat
Meta-analysis was used to combine risk estimates
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doi:10.3389/fphar.2017.00585 Reynolds EH
3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide