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Cureus Sinha R, Papamargaritis D, Sargeant JA, Davies MJ (2023) Efficacy and safety of tirzepatide in type 2 diabetes and obesity management

Rapid, severe hair loss that exceeds what would be expected for telogen effluvium, losing large clumps rather than diffuse thinning, warrants urgent evaluation

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Phase 3 clinical trials are still underway, coming to a close in May 2026

For weight-loss drugs such as retatrutide, this translates to mixing medicine with a larger strategy