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D12492i) male C57BL/6 mice (6 months old) were randomized based on body weight and received pre-treatment of IgG1, GIPR-Ab (5 mg kg 1 ) or GIPR-Ab/GLP-1 (1.5 mg kg 1 ), dosed 24 h before an assay treatment of vehicle or [D-Ala 2 ]-GIP (100 nmol kg 1 , human

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