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The peptides we use have favorable safety profiles when they're dosed correctly under medical supervision, but none of them are FDA-approved for the uses described here, and we don't pretend the risks are zero

The quality of life of these patients declines significantly

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Endogenously, BPC plays a role in maintaining gastric mucosal integrity and homeostasis

131 , e140766 (2021)

Consequently, dual GLP-1/glucagon agonists survodutide, and triple GLP-1/GIP/glucagon agonists retatrutide are not spared gastrointestinal adverse events, as glucagon related pro-emetic signaling may offset any potential tolerability benefits from GIP agonism ( The contribution of amylin-based therapies to gastrointestinal adverse events remains less clear