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The activation of sirtuins, proteins strongly associated with longevity, provides additional anti-aging benefits

CagriSema , Novo Nordisks co-formulation of semaglutide 2.4mg and the long-acting amylin analogue cagrilintide, demonstrated 22.7% body weight reduction in the REDEFINE-1 Phase 3 trial substantially exceeding standalone semaglutide and positioning Novo Nordisk to defend GLP-1 market leadership against tirzepatides superior weight loss profile

Understanding these medications and providing informed consent is essential for a safe treatment experience

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Ethical Approval The study was submitted to the Ethics Committee of 12 de Octubre Hospital (Madrid, Spain), which judged that, due to the nature of the study, further approval was not required