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A study involving children and adolescents with obesity found that non-responders (defined as subjects whose BMI z-score was maintained or increased) to nutritional or exercise regimens had significantly increased choline and a decreased B/C ratio after 6 months

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Atypical beta-adrenoceptor on brown adipocytes as target for anti-obesity drugs

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Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects

Although there are many GLP-1 binding sites in the brain, the half-life of endogenous GLP-1 secreted from the gut is too short to reach the brain owing to the rapid degradation