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NICE recommends considering bariatric surgery for patients with BMI 40 kg/m (or 35 kg/m with comorbidities) who have not achieved adequate weight loss with non-surgical methods

These antibodies can neutralize the peptides intended effect, but they can also, in some cases, cross-react with endogenous peptides the body produces naturally, leading to consequences that are difficult to predict and may take months to manifest

2022, doi: 10.15277/bjd.2022.336

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