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Methods Study design and PLIS cohort Participants of the risk-stratified, randomized, controlled and multicenter PLIS were recruited between 1 March 2012 and 31 August 2016 to assess potential superiority of an intensified LI compared to conventional DPP-based LI in improving glucose tolerance in people with prediabetes at high risk for T2D development

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With varying dosing schedules, effectiveness, and additional mechanisms of action (like Mounjaros GIP activity), each medication offers unique advantages

Additionally, although rare, there have been reports linking green tea extract supplementation to liver-related issues, particularly in individuals with sensitive metabolisms or those taking high doses for extended periods (Saha et al., 2024)

(Reporting by Stephane Mah , Zhifan Liu, Dominique Vidalon