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Shishko et al

Natural supplements for COVID19background, rationale, and clinical trials

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Troca-Marin, J

Following treatment with You-Gui-Wan, a reversal in the composition of the intestinal microbiota was noted, accompanied by a restoration of metabolite levels including acetylcarnitine, tryptophan, n-leucine, isoleucine, betaine, methionine, and valine (Hsu et al., 2021), and it may reduce Der p-induced inflammation and regulate Th1/ Th2 immune disorders by down-regulating TGF- , IL-4, IL-5, IL-13 and inhibiting NF-B activation and up-regulating IL-12 (Lin et al., 2012)