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Increases SIRT-1 activity as a result of enhanced NAD+ salvage, leading to beneficial epigenetic and metabolic reprogramming, including increased oxidative phosphorylation (OXPHOS) and muscle stem cell activation 1-3

Neuroimaging Clin N Am 31(3):327-335, 2021

This means that while its origin is rooted in a natural biological component, the compound itself is a manufactured entity, which has significant implications for its classification and oversight by regulatory bodies

A.FengW

NR works better than NMN (another common precursor) at increasing NAD+ levels because cells absorb it more efficiently

ROUBENNE L, LAISN M, BENOIST D, et al