Sources Blundell, J., Finlayson, G., Axelsen, M., Flint, A., Gibbons, C., Kvist, T., & Hjerpsted, J
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Ionica M, Aburel OM, Vaduva A, Petrus A, Raiu S, Olariu S, Sturza A, Muntean DM (2020) Vitamin D alleviates oxidative stress in adipose tissue and mesenteric vessels from obese patients with subclinical inflammation

The guidelines state, Anesthesiologists should recognize that these conditions can increase the likelihood of regurgitation and pulmonary aspiration and should modify these guidelines based upon their clinical judgment. A previous version states, The guidelines may not apply to, or may need to be modified for, patients with coexisting diseases or conditions that can affect gastric emptying or fluid volume (e.g., pregnancy, obesity, diabetes, hiatal hernia, gastroesophageal reflux disease, ileus or bowel obstruction, emergency care, or enteral tube feeding) and patients in whom airway management might be difficult. Requiring patients to abstain from food for longer than 8 hours, even if the optimal duration was unknown, would have been the most cautious approach, even if it was unenjoyable for patients
Because here's what I've never heard anyone in the GLP-1 conversation say: this emotional flatness isn't new
Patients with A1C 8% at screening had their background basal insulin dose reduced by 20% at the start of the trial to limit potential risk of hypoglycemia