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This also promotes the buildup of S, mitochondrial dysfunction, and increases neuronal loss

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Monitor renal function when prescribing ORLISTAT to patients at increased risk for oxalate nephropathy, including patients with renal impairment and in those with a history of hyperoxaluria or calcium oxalate nephrolithiasis

The FDA, ADA, and AACE do not support the use of this combination in patients with type 2 diabetes