significant weight reduction (~ 710%) through calorie restriction, with or without exercise, and bariatric/metabolic surgery results in high turnover bone loss
Taylor & Francis Online Lincoff AM, et al
It also affects motivation and decision-making in ways that make consistent dietary habits harder to maintain
Meanwhile, the 25-mg dose, which can be used for young patients or those weighing less than 40 kg, will be available in late first quarter or early second quarter next year
Greater doses provided greater weight loss and caused more side effects such as upset stomach and, in rare instances, dysesthesia (2.3%4.5% of those enrolled)
Cardiac effects have not been described in clinical studies with type 2 diabetic subjects