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You tolerate the medication well without persistent nausea, fatigue, or other quality-of-life impacts

The oral formulation boosts incretin activity by approximately 40%, slows gastric emptying, and initiates appetite suppression within the first week

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3.3 PI3K/Akt pathway GLP-1RAs can also function through the Phosphoinositide 3-kinases (PI3K)/AKT pathway (6567)

Instead of increasing GLP-1 activity, it blocks or reduces it