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Side effects of 4-week oral glutathione (1 g/day) in clinical trials included [91]: Flatulence Loose stools Flushing Weight gain Side effects of higher doses (up to around 150 mg/kg/day) in people with cystic fibrosis included chest tightness, diarrhea, and fever

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Neither berberine alone nor tirzepatide alone has a strong propensity to cause hypoglycemia in people with normal pancreatic function who are not also taking insulin or secretagogues

Am J Physiol Regul Integr Comp Physiol (2001) 280(4):R114954.10.1152/ajpregu.2001.280.4.R1149 108 TravagliRAHermannGEBrowningKNRogersRC

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The following doses have been studied in scientific research: BY MOUTH: For treating type 2 diabetes and improving symptoms such as burning, pain, and numbness in the legs and arms: 600 or 1200 mg daily