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In the current HepG2 cell model, in which prolonged exposure is not feasible, the use of relatively high QI concentrations in a short timeframe allows for the identification of underlying mechanisms and pathways, as has been done previously in similar studies with hepatic toxicants (Tafazoli and OBrien, 2009

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Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res 53 Suppl 3:4651

"Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing"