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Diabetes increases the risk of dementia in older diabetes individuals and predisposes people to cognitive impairment

The GLP-1 receptor agonist liraglutide was able to reduce Bax expression in pancreatic cells from T2DM rats, and Bcl-2 expression was increased, islet tissue structure was improved, insulin-positive expression was increased, and -cell apoptosis was reduced (Liu et al., 2021)

This prolonged retention might increase intragastric pressure and potentially promote retrograde movement of gastric contents into the esophagus, particularly in patients with pre-existing lower esophageal sphincter dysfunction or hiatal hernia

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[00035] "Amine" as used herein refers to organic compounds and functional groups that contain a basic nitrogen atom