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Glatter: Additional approaches to lose weight and manage cardiometabolic aspects of obesity include adherence to the Mediterranean, DASH, or MIND diet, along with adequate strength training, close monitoring of hydration status, and caloric intake to maintain and prevent muscle loss, particularly while taking a GLP-1

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About half of employers will offer a cancer COE in 2026, and another 23% are considering doing so by 2028.Figure 7: Conditions Driving Costs, 2023-2025Figure 8: Cancer Screening Measures, 2025-2026 8 | A vast majority of employers have seen an increase in mental health services used by employees, resulting in mental health emerging as a cost driver

doi: 10.1056/NEJMc2023284 56 ZhongPZengHHuangMFuWChenZ

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Whereas GLP-1 monotherapy slightly reduced plasma aspartate aminotransferase (AST) levels compared with those in MK-801-treated mice, GLP-1MK-801 treatment did not affect plasma AST or alanine transaminase (ALT) levels (Extended Data Fig